Sitokin Bagian 2

Kemokin

Kemokin merupakan kelompok kecil sitokin atau protein sinyal yang dipancarkan oleh sel. Sedangkan menurut Wikipedia Kemokin adalah keluarga sitokin kecil, atau protein pemberi sinyal yang disekresikan oleh sel. Dinamai kemokin karena kemampuannya memicu kemotaksis terkordinasi dalam sel berdekatan; atau bisa disebut sebagai sitokin kemotaktik.

Protein sitokin diklasifikasikan sebagai kemokin sesuai dengan perilaku dan karakteristik strukturalnya. Selain dikenal karena mengintervensi kemotaksis, semua kemokin memiliki berat molekul sekitar 8-10 kilo Dalton dan memiliki empat sistein bertumpuk ​​di lokasi yang dijaga agar tetap dalam bentuk 3 dimensi.

Protein ini dikenal di bawah beberapa nama lain termasuk keluarga sitokin SIS, keluarga sitokin SIG, keluarga sitokin SCY, superfamili trombosit faktor-4  atau interkrin. Beberapa kemokin dipandang sebagai pro-inflamasi dan dapat diminta selama respon imun untuk merekrut sel-sel sistem immun tubuh ke tempat infeksi, sementara yang lain dipandang sebagai homeostatik dan terlibat dengan mengendalikan relokasi sel di tengah prosedur normal. Kemokin ditemukan di semua vertebrata, beberapa virus dan beberapa bakteri.

Kemokin telah diklasifikasikan menjadi empat subfamili prinsip: CXC, CC, CX3C dan XC. Protein ini menggunakan dampak organik dengan bekerja sama dengan reseptor transmembran terkoneksi protein G yang disebut reseptor kemokin yang secara khusus ditemukan pada permukaan sel target.

Berikut merupakan katalog Elabscience untuk penelitian yang berkaitan dengan kemokin.

Produk Populer

Catalogue NumberProduct nameDetection Range
E-EL-H0020Human MCP-1(Monocyte Chemotactic Protein 1) ELISA Kit15.625~1000pg/mL
E-EL-H0021Human MIP-1α(Macrophage Inflammatory Protein 1 Alpha) ELISA Kit23.4375~1500pg/mL
E-EL-H0022Human MIP-1β(Macrophage Inflammatory Protein 1 Beta) ELISA Kit31.25~2000pg/mL
E-EL-H0023Human RANTES(Regulated On Activation, Normal T-Cell Expressed and Secreted) ELISA Kit31.25~2000pg/mL
E-EL-H0025Human ECF/CCL11(Eosinophil Chemotactic Factor) ELISA Kit15.625~1000pg/mL
E-EL-H0026Human TARC(Thymus Activation Regulated Chemokine) ELISA Kit31.25~2000pg/mL
E-EL-H0027Human MIP-3α(Macrophage Inflammatory Protein 3 Alpha) ELISA Kit15.625~1000pg/mL
E-EL-H0028Human SLC(Secondary Lymphoid Tissue Chemokine) ELISA Kit78.125~5000pg/mL
E-EL-H0029Human MDC/CCL22(Macrophage-Derived Chemokine) ELISA Kit62.5~4000pg/mL
E-EL-H0030Human MPIF2(Myeloid Progenitor Inhibitory Factor 2) ELISA Kit78.125~5000pg/mL
E-EL-H0031Human MIP4α(Macrophage Inflammatory Protein 4 Alpha) ELISA Kit31.25~2000pg/mL
E-EL-H0032Human CTACK(Cutaneous T-cell Attracting Chemokine) ELISA Kit15.625~1000pg/mL
E-EL-H0044Human CX3CL1(Chemokine C-X3-C-Motif Ligand 1) ELISA Kit0.15625~10ng/mL
E-EL-H0045Human GROα/CXCL1(Growth Regulated Oncogene Alpha) ELISA Kit15.625~1000pg/mL
E-EL-H0046Human ENA-78/CXCL5(Epithelial Neutrophil Activating Peptide 78) ELISA Kit31.25~2000pg/mL
E-EL-H0047Human GCP-2(Granulocyte Chemotactic Protein 2) ELISA Kit31.25~2000pg/mL
E-EL-H0048Human IL-8(Interleukin 8) ELISA Kit31.25~2000pg/mL
E-EL-H0050Human IP-10/CXCL10(Interferon Gamma Induced Protein 10kDa) ELISA Kit7.8125~500pg/mL
E-EL-H0051Human I-TAC/CXCL11(Interferon Inducible T-cell Alpha Chemoattractant) ELISA Kit62.5~4000pg/mL
E-EL-H0052Human SDF-1/CXCL12(Stromal Cell Derived Factor 1) ELISA Kit0.15625~10ng/mL
E-EL-H0053Human BLC(B-Lymphocyte Chemoattractant) ELISA Kit15.625~1000pg/mL
E-EL-H0054Human CXCL16(Chemokine C-X-C-Motif Ligand 16) ELISA Kit0.15625~10ng/mL
E-EL-H0600Human BRAK/CXCL14(Breast and Kidney Expressed Chemokine) ELISA Kit0.15625~10ng/mL
E-EL-H0679Human CCR1(CC-Chemokine Receptor 1) ELISA Kit0.3125~20ng/mL
E-EL-H0699Human CCL1(Chemokine C-C-Motif Ligand 1) ELISA Kit31.25~2000pg/mL
E-EL-H0700Human CCL14(Chemokine C-C-Motif Ligand 14) ELISA Kit15.625~1000pg/mL
E-EL-H0701Human CCL16(Chemokine C-C-Motif Ligand 16) ELISA Kit0.15625~10ng/mL
E-EL-H0702Human CCL3L1(Chemokine C-C-Motif Ligand 3 Like Protein 1) ELISA Kit78.125~5000pg/mL
E-EL-H0703Human CCL4L1(Chemokine C-C-Motif Ligand 4 Like Protein 1) ELISA Kit15.625~1000pg/mL
E-EL-H0704Human CCR8(Chemokine C-C-Motif Receptor 8) ELISA Kit0.15625~10ng/mL
E-EL-H0707Human CX3CR1(Chemokine C-X3-C-Motif Receptor 1) ELISA Kit15.625~1000pg/mL
E-EL-H0714Human CKLF(Chemokine Like Factor) ELISA Kit125~8000pg/mL
E-EL-H0853Human CXCR1(CXC-Chemokine Receptor 1) ELISA Kit0.3125~20ng/mL
E-EL-H0854Human CXCR3(CXC-Chemokine Receptor 3) ELISA Kit0.15625~10ng/mL
E-EL-H0962Human XCR1(XC-Chemokine Receptor 1) ELISA Kit0.15625~10ng/mL
E-EL-H1009Human MIγ/CXCL9(Monocyte Interferon Gamma Inducing Factor) ELISA Kit0.15625~10ng/mL
E-EL-H1158Human MCP-2/CCL8(Monocyte Chemotactic Protein 2) ELISA Kit6.25~400pg/mL
E-EL-H1159Human MCP-4/CCL13(Monocyte Chemotactic Protein 4) ELISA Kit15.625~1000pg/mL
E-EL-H1270Human PARC/CCL18(Pulmonary Activation Regulated Chemokine) ELISA Kit78.125~5000pg/mL
E-EL-H1348Human MPIF-1/CCL23(Myeloid Progenitor Inhibitory Factor 1) ELISA Kit15.625~1000pg/mL
E-EL-H1528Human MIP-3β/ELC/CCL19(Macrophage Inflammatory Protein 3β) ELISA Kit15.625~1000pg/mL
E-EL-H1691Human Lptn/XCL1(Lymphotactin) ELISA Kit62.5~4000pg/mL
E-EL-H1877Human CCR2(Chemokine C-C-Motif Receptor 2) ELISA Kit0.15625~10ng/mL
E-EL-H1904Human GROβ/CXCL2(Growth Regulated Oncogene Beta) ELISA Kit15.625~1000pg/mL
E-EL-H1905Human GROγ/CXCL3(Growth Regulated Oncogene Gamma) ELISA Kit7.8125~500pg/mL
E-EL-H2144Human TECK/CCL25(Thymus Expressed Chemokine) ELISA Kit62.5~4000pg/mL
E-EL-H2216Human PF4(Platelet Factor 4) ELISA Kit1.5625~100ng/mL
E-EL-H2282Human MEC/CCL28(Mucosae Associated Epithelia Chemokine) ELISA Kit0.3125~20ng/mL
E-EL-H2578Human CXCR2(CXC-Chemokine Receptor 2) ELISA Kit0.78125~50ng/mL
E-EL-H5489Human CCR4(Chemokine C-C-Motif Receptor 4) ELISA Kit78.125~5000pg/mL
E-EL-H5490Human CXCR4(Chemokine C-X-C-Motif Receptor 4) ELISA Kit78.125~5000pg/mL

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